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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR35
All Species:
27.58
Human Site:
T580
Identified Species:
55.15
UniProt:
Q9P2L0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2L0
NP_001006658.1
1181
133547
T580
D
A
R
V
T
D
S
T
G
Q
Q
V
V
G
E
Chimpanzee
Pan troglodytes
XP_515315
1273
143538
T672
D
A
R
V
T
D
S
T
G
Q
Q
I
V
G
E
Rhesus Macaque
Macaca mulatta
XP_001107482
1296
146192
T695
D
A
R
V
T
D
S
T
G
Q
Q
V
V
G
E
Dog
Lupus familis
XP_532884
1356
153148
T580
D
A
R
V
T
D
S
T
G
Q
Q
V
T
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BND3
1181
133947
T580
D
T
R
V
T
D
S
T
G
Q
Q
V
V
G
E
Rat
Rattus norvegicus
NP_001092810
1170
132761
T569
D
T
R
V
T
D
S
T
G
Q
Q
V
V
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511461
679
76765
S145
Q
L
C
H
V
A
W
S
S
D
S
K
I
L
L
Chicken
Gallus gallus
XP_419970
1197
135555
T599
D
A
R
V
T
S
S
T
G
Q
Q
V
I
G
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139061
1203
136070
D600
E
T
R
G
S
M
G
D
A
E
G
G
S
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647653
1205
135183
T587
I
D
H
M
G
V
M
T
L
L
D
L
D
D
N
Honey Bee
Apis mellifera
XP_394812
1185
134241
D585
I
S
K
D
E
E
S
D
N
E
I
N
K
F
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783217
1209
136043
E597
D
T
K
W
V
N
P
E
G
Q
E
I
I
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
89.8
82
N.A.
92.2
91.7
N.A.
51.1
84.4
N.A.
78
N.A.
47.2
51.9
N.A.
66.3
Protein Similarity:
100
92.6
90.6
84.7
N.A.
96.7
96
N.A.
54.4
92.2
N.A.
88.4
N.A.
64.9
70.6
N.A.
80.5
P-Site Identity:
100
93.3
100
93.3
N.A.
93.3
93.3
N.A.
0
86.6
N.A.
6.6
N.A.
6.6
13.3
N.A.
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
13.3
93.3
N.A.
26.6
N.A.
20
40
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
42
0
0
0
9
0
0
9
0
0
0
0
0
9
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
9
0
9
0
50
0
17
0
9
9
0
9
9
0
% D
% Glu:
9
0
0
0
9
9
0
9
0
17
9
0
0
0
67
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
9
9
0
9
0
67
0
9
9
0
67
0
% G
% His:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
0
0
0
0
9
17
25
0
0
% I
% Lys:
0
0
17
0
0
0
0
0
0
0
0
9
9
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
9
9
0
9
0
9
9
% L
% Met:
0
0
0
9
0
9
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
9
0
0
9
0
0
9
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
67
59
0
0
0
9
% Q
% Arg:
0
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
0
9
9
67
9
9
0
9
0
9
0
0
% S
% Thr:
0
34
0
0
59
0
0
67
0
0
0
0
9
9
0
% T
% Val:
0
0
0
59
17
9
0
0
0
0
0
50
42
0
0
% V
% Trp:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _